Neurotransmitters and other chemical signalling agents
| SUBSTANCE P (SP) AND NEUROKININS A AND B (NKA, NKB) | |||
|---|---|---|---|
| Precursors: | Preprotachykinins | ||
| Synthesising enzymes: | Peptidases | ||
| Metabolising enzymes: | ACh-esterase, EC 24.11 | ||
| Metabolite: | Peptide fragments | ||
| Receptor subtypes | Agonists | Antagonists | Second messenger |
| NK(1) | SPOMe, GR 73632, Sar9Met(O2)11SP |
GR82334, RP67580, CP-99994 |
PI |
| NK(2) | GR 64349 | L-659877, SR48968, MEN10207, GR94800 GR100679 |
PI |
| NK(3) | Senktide | GR138676 | PI |
Reviews
Maggio (1988) Ann. Rev. Neurosci. 11, 13-28.
Nakanishi, S. (1991) Ann. Rev. Neurosci. 14, 123-136.
Other neurotransmitters and neurohormones
Prostanoids
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