Neurotransmitters and other chemical signalling agents
| GLYCINE | |||
|---|---|---|---|
| Precursors: | None | ||
| Synthesising enzymes: | None | ||
| Metabolising enzymes: | None (uptake is more important) | ||
| Metabolite: | None | ||
| Receptor subtypes | Agonists | Antagonists | Second messenger |
| Glycine | Glycine | Strychnine | (+ve)gCl- |
| Allosteric site on NMDA receptor |
Glycine | 7-chloro-kynurenate | n/a |
NB: (+ve) indicates increase; (-ve) indicates decrease.
Reviews
Barron, S.E. and Guth, P.S. (1987) Trends Pharmacol. Sci. 8, 204-206.
Lodge, D. and Johnson, K.M. (1990) Trends Pharmacol. Sci. 11, 81-86.
Histamine
Glutamate
and Aspartate
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