Glaxo Wellcome and Science

Molecular pharmacology: definitions

The identification of receptor subtypes has been revolutionised by the techniques of molecular biology, which have enabled the genes for many receptors to be identified and cloned. The glossary below explains the terms which describe this technology.

Index

3 prime end (3')	5 prime end (5')	Alternative RNA splicing
Annealing	Anticoding DNA strand	Anticodon
Antisense strand	Base pair	cDNA
cDNA Library	Central dogma	Clone
Cloning vector	Coding DNA strand	Codon
Cosmid vector	Cos site	Denaturation
Domain	DNA	DNase
DNase 1	DNA ligase	DNA polymerase 1
Dot blotting	Endonuclease	Exon
Exonuclease	Expression	Expression Vector
Genome	Genomic library	Hybridization
Inducer	In situ hybridization	Intron
Library	Ligation	mRNA
Nick translation	Nonsense codons	Northern Blot
Nuclease S1	Nucleotide	Oligonucleotide
Oncogene	Operon	PCR
Phage	Plasmid	Poly-A tail
Primer	Probe	Promoter region
Proto-oncogene	Recombinant DNA	Repressor
Restriction enzyme	Restriction map	Retrovirus
Reverse transcriptase	RNA	RNA polymerase
RNase	RNA splicing	rRNA
Sense Strand	Southern Blot	Split gene
Transcription	Transduction	Transfection
Translation	tRNA	Vector
Western Blot

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